Capsule, Generic Name: Silymarin USP, Manufacturer: Incepta Pharmaceuticals Ltd.
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Indications
Silymarin (Milk Thistle) is used to treat and prevent the following conditions:
Liver disease, (non-alcoholic & alcoholic)
Liver cirrhosis, (non-alcoholic & alcoholic)
Infectious hepatitis
Drug-induced hepatitis
Liver disease secondary to diabetes mellitus
Toxicity of narcotics
Fatty liver
Jaundice
Pharmacology
The physiologically active component is Silymarin, a flavonoid compound derived from Silybum marianum, often known as Milk thistle. It protects the hepatocellular membrane from toxins, increases protein synthesis, antioxidant activity, anti-fibrotic activity, and may have anti-inflammatory or immunomodulatory effects.
Dosage & Administration
1 capsule 2 to 3 times daily or as directed by a physician.
Interaction
The combination of silymarin with butyrophenones or phenothiazines has been shown to reduce lipid peroxidation.
Contraindications
In patients who have a known allergy to silymarin, this medication is contraindicated.
Side Effects
In the indicated dose, it is well tolerated. A modest laxative effect may be observed on rare occasions.
Pregnancy & Lactation
There is no data on the usage of Silymarin 70 mg or 140 mg during pregnancy or breastfeeding. As a result, if needed, Silymarin 70 mg or 140 mg should be taken with caution and in accordance with the doctor's instructions.
Therapeutic Class
Herbal and nutraceuticals, Cholagogues, Cholelitholytics, and Hepatic Protectors
Storage Conditions
Keep cool and dry, away from light and moisture. Keep out of children's reach.
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